Version 5.4
Homo sapiens Gene: EXTL2
Summary
InnateDB Gene IDBG-100534.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXTL2
Gene Name exostoses (multiple)-like 2
Synonyms EXTR2
Species Homo sapiens
Ensembl Gene ENSG00000162694
Encoded Proteins
IDBP-100536
exostoses (multiple)-like 2
IDBP-100538
exostoses (multiple)-like 2
IDBP-387210
exostoses (multiple)-like 2
IDBP-387211
exostoses (multiple)-like 2
IDBP-595646
exostoses (multiple)-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:100872372-100895998
Strand Reverse strand
Band p21.2
Transcripts
ENST00000370114 ENSP00000359132
ENST00000370113 ENSP00000359131
ENST00000450240 ENSP00000403363
ENST00000416479 ENSP00000392255
ENST00000494907
ENST00000480774
ENST00000535414 ENSP00000444385
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006044 N-acetylglucosamine metabolic process
GO:0008152 metabolic process
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0019276 UDP-N-acetylgalactosamine metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027963
View Gene Order
ENSBTAG00000019026
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00534
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.357637 Hs.617053 Hs.713048
RefSeq NM_001033025 NM_001261440 NM_001261441 NM_001261442 NM_001439 XM_005270621 XM_005270622
HUGO
OMIM
CCDS CCDS72831 CCDS775
HPRD 03876
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca