Version 5.4
Homo sapiens Gene: MAGI3
Summary
InnateDB Gene IDBG-101198.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGI3
Gene Name membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000081026
Encoded Proteins
IDBP-101200
membrane associated guanylate kinase, WW and PDZ domain containing 3
IDBP-101202
membrane associated guanylate kinase, WW and PDZ domain containing 3
IDBP-101204
membrane associated guanylate kinase, WW and PDZ domain containing 3
IDBP-101206
membrane associated guanylate kinase, WW and PDZ domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:113390749-113685923
Strand Forward strand
Band p13.2
Transcripts
ENST00000369617 ENSP00000358630
ENST00000307546 ENSP00000304604
ENST00000369615 ENSP00000358628
ENST00000369611 ENSP00000358624
ENST00000486456
ENST00000477955
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004385 guanylate kinase activity
GO:0005109 frizzled binding
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0006915 apoptotic process
GO:0016032 viral process
GO:0035556 intracellular signal transduction
GO:0043507 positive regulation of JUN kinase activity
GO:0046939 nucleotide phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005923 tight junction
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052539
View Gene Order
ENSBTAG00000019611
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.486189 Hs.601862 Hs.671777
RefSeq NM_001142782 NM_152900 XM_005270737
HUGO
OMIM
CCDS CCDS44196 CCDS860
HPRD 11290
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca