Version 5.4
| Homo sapiens Gene: SRGAP2B | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-101590.7 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | SRGAP2B | ||||||||||||
| Gene Name | SLIT-ROBO Rho GTPase activating protein 2B (pseudogene) | ||||||||||||
| Synonyms | |||||||||||||
| Species | Homo sapiens | ||||||||||||
| Ensembl Gene | ENSG00000196369 | ||||||||||||
| Encoded Proteins |
SLIT-ROBO Rho GTPase activating protein 2B
SLIT-ROBO Rho GTPase activating protein 2B
SLIT-ROBO Rho GTPase activating protein 2B
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from incomplete segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2 locus. The encoded protein lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating protein 2. The functionality of the protein encoded by this locus has been questioned, as several normal individuals with homozygous deletions for this locus have been identified, and the expression of this locus appears to be much lower than the similar SLIT-ROBO Rho GTPase activating protein 2C (SRGAP2C) locus. The SRGAP2C locus has been shown to encode a protein that functions antagonistically to SLIT-ROBO Rho GTPase activating protein 2 in cortical neuron development. [provided by RefSeq, Dec 2012] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 1:144887265-145095528 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | q21.1 | ||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Orthologs | |||||||||||||
| No orthologs found for this gene | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | |||||||||||||
| UniGene | Hs.743217 | ||||||||||||
| RefSeq | NM_001271870 XM_005277419 XM_005277420 XM_005277421 XM_005277422 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS72854 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | |||||||||||||
| GenPept | |||||||||||||
| RNA Seq Atlas | |||||||||||||