Version 5.4
Homo sapiens Gene: CELF3
Summary
InnateDB Gene IDBG-102401.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CELF3
Gene Name CUGBP, Elav-like family member 3
Synonyms BRUNOL1; CAGH4; ERDA4; ETR-1; TNRC4
Species Homo sapiens
Ensembl Gene ENSG00000159409
Encoded Proteins
IDBP-102405
CUGBP, Elav-like family member 3
IDBP-102407
CUGBP, Elav-like family member 3
IDBP-388598
CUGBP, Elav-like family member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151702404-151716814
Strand Reverse strand
Band q21.3
Transcripts
ENST00000290583 ENSP00000290583
ENST00000290585 ENSP00000290585
ENST00000419910
ENST00000420342 ENSP00000402503
ENST00000470688
ENST00000479893
ENST00000478829
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0007283 spermatogenesis
GO:0008380 RNA splicing
GO:0030317 sperm motility
GO:0048026 positive regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028137
View Gene Order
ENSBTAG00000019131
Not yet available
Cross-References
SwissProt Q5SZQ8
TrEMBL B4DQL3 Q8IZ97
UniProt Splice Variant
Entrez Gene 11189
UniGene Hs.26047 Hs.641801
RefSeq NM_001172648 NM_001172649 NM_001291106 NM_001291107 NM_007185 XM_006711139 XM_006711141
HUGO HGNC:11967
OMIM 612678
CCDS CCDS1002 CCDS53367
HPRD
IMGT
EMBL AF284423 AF329264 AK298852 AL589765 AY165003 AY165053 BC052491 BC068008 BC104758 BC143226 CH471121 U80746
GenPept AAB91444 AAG14457 AAH52491 AAH68008 AAI04759 AAI43227 AAK07474 AAN73884 AAN73886 BAG60975 CAI17166 EAW53422
RNA Seq Atlas 11189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca