Homo sapiens Gene: MRPL9
Summary
InnateDB Gene IDBG-102413.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPL9
Gene Name mitochondrial ribosomal protein L9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143436
Encoded Proteins
mitochondrial ribosomal protein L9
mitochondrial ribosomal protein L9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 8q21.11. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151759643-151763564
Strand Reverse strand
Band q21.3
Transcripts
ENST00000368830 ENSP00000357823
ENST00000368829 ENSP00000357822
ENST00000467306
ENST00000468006
ENST00000495867
ENST00000478926
ENST00000486707
ENST00000492684
ENST00000481777
ENST00000461182
ENST00000462783
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005761 mitochondrial ribosome
GO:0005840 ribosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001300733 NM_031420 XM_005245455
HUGO
OMIM
CCDS CCDS1003 CCDS72916
HPRD 14774
IMGT
EMBL
GenPept
RNA Seq Atlas