Version 5.4
Homo sapiens Gene: PMF1
Summary
InnateDB Gene IDBG-103415.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PMF1
Gene Name polyamine-modulated factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160783
Encoded Proteins
IDBP-103419
polyamine-modulated factor 1
IDBP-103421
polyamine-modulated factor 1
IDBP-103427
polyamine-modulated factor 1
IDBP-813217
polyamine-modulated factor 1
IDBP-813228
polyamine-modulated factor 1
IDBP-721567
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring PMF1 (polyamine-modulated factor 1) and BGLAP (bone gamma-carboxyglutamate Gla protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants encoding isoforms that share sequence identity with the upstream gene product, but they contain distinct C-termini due to frameshifts versus the downstream gene coding sequence. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:156212993-156240042
Strand Forward strand
Band q22
Transcripts
ENST00000368279 ENSP00000357262
ENST00000368277 ENSP00000357260
ENST00000368273 ENSP00000357256
ENST00000466489 ENSP00000476770
ENST00000497069 ENSP00000476760
ENST00000567140 ENSP00000458021
ENST00000606952
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0043522 leucine zipper domain binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
Cellular Component
GO:0000444 MIS12/MIND type complex
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028066
View Gene Order
ENSBTAG00000009432
Not yet available
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 11243
UniGene
RefSeq NM_001199653 NM_001199654 NM_007221 NM_001199661 NM_001199662 NM_001199663 NM_001199664
HUGO HGNC:9112
OMIM 609176
CCDS CCDS30886 CCDS55648 CCDS55649 CCDS55650 CCDS55651 CCDS60299 CCDS72944
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 11243

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca