Version 5.4
Homo sapiens Gene: FCRL5
Summary
InnateDB Gene IDBG-103665.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCRL5
Gene Name Fc receptor-like 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143297
Encoded Proteins
IDBP-103667
Fc receptor-like 5
IDBP-103673
Fc receptor-like 5
IDBP-103675
Fc receptor-like 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:157513377-157552520
Strand Reverse strand
Band q23.1
Transcripts
ENST00000361835 ENSP00000354691
ENST00000368190 ENSP00000357173
ENST00000368189 ENSP00000357172
ENST00000462218
ENST00000497286
ENST00000461387
ENST00000483875
ENST00000481082
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0050859 negative regulation of B cell receptor signaling pathway
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q96RD9
TrEMBL
UniProt Splice Variant
Entrez Gene 83416
UniGene Hs.415950
RefSeq NM_001195388 NM_031281
HUGO HGNC:18508
OMIM 605877
CCDS CCDS1165
HPRD
IMGT
EMBL AF343662 AF343663 AF343664 AF343665 AF369794 AF397453 AL135929 AL353899 AL834187 AY358085 BC101066 BC101067 BC101069 EF064730
GenPept AAI01067 AAI01068 AAI01070 AAK31325 AAK31326 AAK31327 AAK31328 AAK50059 AAK93971 AAQ88452 ABK41913 CAH56486 CAH71427
RNA Seq Atlas 83416

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca