Version 5.4
Homo sapiens Gene: FCRLB
Summary
InnateDB Gene IDBG-104342.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCRLB
Gene Name Fc receptor-like B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162746
Encoded Proteins
IDBP-104344
Fc receptor-like B
IDBP-104346
Fc receptor-like B
IDBP-104348
Fc receptor-like B
IDBP-104350
Fc receptor-like B
IDBP-104352
Fc receptor-like B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:161721563-161728143
Strand Forward strand
Band q23.3
Transcripts
ENST00000367948 ENSP00000356925
ENST00000336830 ENSP00000338598
ENST00000367944 ENSP00000356921
ENST00000367946 ENSP00000356923
ENST00000367945 ENSP00000356922
ENST00000495397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0050777 negative regulation of immune response
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070524
View Gene Order
ENSBTAG00000014580
Not yet available
Cross-References
SwissProt Q6BAA4
TrEMBL
UniProt Splice Variant
Entrez Gene 127943
UniGene Hs.517422
RefSeq NM_001288830 NM_001002901 NM_001288829 NM_001288831 NM_001288832
HUGO HGNC:26431
OMIM 609251
CCDS CCDS72965 CCDS30927 CCDS72962 CCDS72963 CCDS72964
HPRD 08093
IMGT
EMBL AK290733 AL359541 AY670683 AY670684 AY670685 AY670686 AY670687 AY786314 BC038564 DQ021957 EF064728
GenPept AAH38564 AAT77987 AAT77988 AAT77989 AAT77990 AAT77991 AAX11390 AAY42534 ABK41911 BAF83422 CAH74155 CAM20340 CAM20341 CAM20342 CAM20343
RNA Seq Atlas 127943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca