Version 5.4
| Homo sapiens Gene: DNM3 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-104822.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | DNM3 | ||||||||||||||||||
| Gene Name | dynamin 3 | ||||||||||||||||||
| Synonyms | Dyna III | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000197959 | ||||||||||||||||||
| Encoded Proteins |
dynamin 3
dynamin 3
dynamin 3
dynamin 3
dynamin 3
dynamin 3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
Members of the dynamin family, such as DNM3, possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding (Orth and McNiven, 2003 [PubMed 12517701]).[supplied by OMIM, Mar 2008] This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:171841498-172418466 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q24.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Toll Like Receptor 4 (TLR4) Cascade pathway
MHC class II antigen presentation pathway
Retrograde neurotrophin signalling pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
Developmental Biology pathway
Signalling by NGF pathway
Innate Immune System pathway
Toll-Like Receptors Cascades pathway
Axon guidance pathway
Signal Transduction pathway
Adaptive Immune System pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
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| KEGG |
Endocytosis pathway
Bacterial invasion of epithelial cells pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q9UQ16 | ||||||||||||||||||
| TrEMBL | E5RIK2 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 26052 | ||||||||||||||||||
| UniGene | Hs.654775 Hs.675165 Hs.685968 | ||||||||||||||||||
| RefSeq | NM_001136127 NM_015569 NM_001278252 XM_005245081 | ||||||||||||||||||
| HUGO | HGNC:29125 | ||||||||||||||||||
| OMIM | 611445 | ||||||||||||||||||
| CCDS | CCDS44276 CCDS60356 | ||||||||||||||||||
| HPRD | 13241 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AB020627 AL031864 AL121984 AL133514 AL136712 AL137157 AL445990 AL512843 BC064546 CH471067 Z97195 | ||||||||||||||||||
| GenPept | AAH64546 BAA74843 CAB66647 CAH69969 CAH69970 CAH71040 CAH71041 CAH71951 CAH71952 CAH74079 CAH74080 CAI19054 CAI19055 CAI19211 CAI19212 CAI22007 CAI22008 EAW90918 | ||||||||||||||||||
| RNA Seq Atlas | 26052 | ||||||||||||||||||