Version 5.4
Homo sapiens Gene: ANGPTL1
Summary
InnateDB Gene IDBG-105082.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANGPTL1
Gene Name angiopoietin-like 1
Synonyms ANG3; ANGPT3; AngY; ARP1; dJ595C2.2; UNQ162
Species Homo sapiens
Ensembl Gene ENSG00000116194
Encoded Proteins
IDBP-105084
angiopoietin-like 1
IDBP-105086
angiopoietin-like 1
IDBP-389762
angiopoietin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:178849705-178871052
Strand Reverse strand
Band q25.2
Transcripts
ENST00000234816 ENSP00000234816
ENST00000367629 ENSP00000356601
ENST00000444255 ENSP00000392023
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
Biological Process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033544
View Gene Order
ENSBTAG00000010719
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 9068
UniGene Hs.591474 Hs.660962
RefSeq NM_004673
HUGO HGNC:489
OMIM 603874
CCDS CCDS1327
HPRD 04851
IMGT
EMBL
GenPept
RNA Seq Atlas 9068

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca