Version 5.4
Homo sapiens Gene: LPGAT1
Summary
InnateDB Gene IDBG-106521.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LPGAT1
Gene Name lysophosphatidylglycerol acyltransferase 1
Synonyms FAM34A; FAM34A1; NET8
Species Homo sapiens
Ensembl Gene ENSG00000123684
Encoded Proteins
IDBP-106523
lysophosphatidylglycerol acyltransferase 1
IDBP-106525
lysophosphatidylglycerol acyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Acyl-CoA:lysophosphatidylglycerol (LPG) acyltransferase catalyzes the reacylation of LPG to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin (Yang et al., 2004 [PubMed 15485873]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:211743457-211830772
Strand Reverse strand
Band q32.3
Transcripts
ENST00000366997 ENSP00000355964
ENST00000366996 ENSP00000355963
ENST00000498690
ENST00000488600
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006644 phospholipid metabolic process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026623
View Gene Order
ENSBTAG00000005137
Not yet available
Pathways
NETPATH
REACTOME
REACT_121324
Acyl chain remodelling of PG pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.497674 Hs.600772 Hs.608545 Hs.617683 Hs.731420 Hs.741167
RefSeq NM_014873 XM_005273362 XM_005273363 XM_005273364 XM_006711695
HUGO
OMIM
CCDS CCDS31018
HPRD 14304
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca