Version 5.4
Homo sapiens Gene: MARK1
Summary
InnateDB Gene IDBG-106753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARK1
Gene Name MAP/microtubule affinity-regulating kinase 1
Synonyms MARK; Par-1c; Par1c
Species Homo sapiens
Ensembl Gene ENSG00000116141
Encoded Proteins
IDBP-106755
MAP/microtubule affinity-regulating kinase 1
IDBP-106757
MAP/microtubule affinity-regulating kinase 1
IDBP-295740
MAP/microtubule affinity-regulating kinase 1
IDBP-808565
MAP/microtubule affinity-regulating kinase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:220528183-220664461
Strand Forward strand
Band q41
Transcripts
ENST00000366918 ENSP00000355885
ENST00000366917 ENSP00000355884
ENST00000402574 ENSP00000386017
ENST00000485104
ENST00000611084 ENSP00000483424
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0001786 phosphatidylserine binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0050321 tau-protein kinase activity
GO:0070300 phosphatidic acid binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0001764 neuron migration
GO:0006468 protein phosphorylation
GO:0007010 cytoskeleton organization
GO:0016055 Wnt signaling pathway
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026620
View Gene Order
ENSBTAG00000010460
Not yet available
Cross-References
SwissProt Q9P0L2
TrEMBL B4DIB3 X5D2M4
UniProt Splice Variant
Entrez Gene 4139
UniGene Hs.497806 Hs.606426 Hs.609924 Hs.734178
RefSeq NM_001286124 NM_001286126 NM_001286128 NM_018650 XM_005273134 XM_006711326 XM_006711327
HUGO HGNC:6896
OMIM 606511
CCDS CCDS31029 CCDS65789 CCDS73033 CCDS73034
HPRD
IMGT
EMBL AB040910 AC096640 AF154845 AK027493 AK295506 AL592406 BC113869 BC114478 CH471100 KJ534879
GenPept AAF72103 AAI13870 AAI14479 AHW56519 BAA96001 BAB55152 BAG58425 CAH72462 CAH72463 EAW93298 EAW93299 EAW93300 EAW93302
RNA Seq Atlas 4139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca