Version 5.4
Homo sapiens Gene: DNAH14
Summary
InnateDB Gene IDBG-106931.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAH14
Gene Name dynein, axonemal, heavy chain 14
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185842
Encoded Proteins
IDBP-106920
dynein, axonemal, heavy chain 14
IDBP-106922
dynein, axonemal, heavy chain 14
IDBP-106924
dynein, axonemal, heavy chain 14
IDBP-106927
dynein, axonemal, heavy chain 14
IDBP-106933
dynein, axonemal, heavy chain 14
IDBP-227004
dynein, axonemal, heavy chain 14
IDBP-390060
dynein, axonemal, heavy chain 14
IDBP-390061
dynein, axonemal, heavy chain 14
IDBP-390064
dynein, axonemal, heavy chain 14
IDBP-390066
dynein, axonemal, heavy chain 14
IDBP-390069
dynein, axonemal, heavy chain 14
IDBP-390071
dynein, axonemal, heavy chain 14
IDBP-483293
dynein, axonemal, heavy chain 14
IDBP-477064
dynein, axonemal, heavy chain 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:224896262-225399292
Strand Forward strand
Band q42.12
Transcripts
ENST00000366850 ENSP00000355815
ENST00000366849 ENSP00000355814
ENST00000366848 ENSP00000355813
ENST00000328556 ENSP00000332424
ENST00000327794 ENSP00000328980
ENST00000400952 ENSP00000383737
ENST00000445597 ENSP00000409472
ENST00000430092 ENSP00000414402
ENST00000433124 ENSP00000409971
ENST00000453375
ENST00000439375 ENSP00000392061
ENST00000450490 ENSP00000398678
ENST00000428003 ENSP00000414699
ENST00000498360
ENST00000486657
ENST00000474127
ENST00000474801 ENSP00000429568
ENST00000495456 ENSP00000429122
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005929 cilium
GO:0030286 dynein complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.133977
RefSeq NM_001145154 NM_001373 NM_144989
HUGO
OMIM
CCDS CCDS41472 CCDS44322
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca