Homo sapiens Gene: CAPN9 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-107366.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | CAPN9 | ||||||||
Gene Name | calpain 9 | ||||||||
Synonyms | GC36; nCL-4 | ||||||||
Species | Homo sapiens | ||||||||
Ensembl Gene | ENSG00000135773 | ||||||||
Encoded Proteins |
calpain 9
calpain 9
calpain 9
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 1:230747384-230802003 | ||||||||
Strand | Forward strand | ||||||||
Band | q42.2 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Hs.498021 | ||||||||
RefSeq | NM_006615 NM_016452 XM_005273010 | ||||||||
HUGO | |||||||||
OMIM | |||||||||
CCDS | CCDS1586 CCDS31053 | ||||||||
HPRD | 05909 | ||||||||
IMGT | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||