Version 5.4
Homo sapiens Gene: LAP3
Summary
InnateDB Gene IDBG-10959.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LAP3
Gene Name leucine aminopeptidase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000002549
Encoded Proteins
IDBP-10963
leucine aminopeptidase 3
IDBP-479302
leucine aminopeptidase 3
IDBP-477554
leucine aminopeptidase 3
IDBP-809778
leucine aminopeptidase 3
IDBP-809783
leucine aminopeptidase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:17577192-17607972
Strand Forward strand
Band p15.32
Transcripts
ENST00000226299 ENSP00000226299
ENST00000508497
ENST00000512397
ENST00000509583 ENSP00000423350
ENST00000507960
ENST00000508014
ENST00000513105 ENSP00000424724
ENST00000504614
ENST00000503467
ENST00000606142 ENSP00000476028
ENST00000618908 ENSP00000481000
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008233 peptidase activity
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005802 trans-Golgi network
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039682
View Gene Order
ENSBTAG00000005989
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00330
Arginine and proline metabolism pathway
hsa00480
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.570791
RefSeq NM_015907
HUGO
OMIM
CCDS CCDS3422
HPRD 07516
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca