Version 5.4
Homo sapiens Gene: MED28
Summary
InnateDB Gene IDBG-11074.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED28
Gene Name mediator complex subunit 28
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000118579
Encoded Proteins
IDBP-11076
mediator complex subunit 28
IDBP-483975
mediator complex subunit 28
IDBP-810358
mediator complex subunit 28
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:17614631-17634105
Strand Forward strand
Band p15.32
Transcripts
ENST00000237380 ENSP00000237380
ENST00000506409
ENST00000503945 ENSP00000426529
ENST00000612711 ENSP00000483496
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 106 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 106 [view]
Protein-Protein 105 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019827 stem cell maintenance
GO:0051151 negative regulation of smooth muscle cell differentiation
Cellular Component
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0016592 mediator complex
GO:0030864 cortical actin cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015804
View Gene Order
ENSBTAG00000019441
Not yet available
Cross-References
SwissProt
TrEMBL H0YAA8
UniProt Splice Variant
Entrez Gene 80306
UniGene Hs.605260
RefSeq NM_025205
HUGO HGNC:24628
OMIM 610311
CCDS CCDS33963
HPRD 14381
IMGT
EMBL AC006160
GenPept
RNA Seq Atlas 80306

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca