Version 5.4
Homo sapiens Gene: UPK3A
Summary
InnateDB Gene IDBG-11393.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UPK3A
Gene Name uroplakin 3A
Synonyms UP3A; UPIII; UPIIIA; UPK3
Species Homo sapiens
Ensembl Gene ENSG00000100373
Encoded Proteins
IDBP-11395
uroplakin 3A
IDBP-238234
uroplakin 3A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:45284982-45295874
Strand Forward strand
Band q13.31
Transcripts
ENST00000216211 ENSP00000216211
ENST00000396082 ENSP00000379391
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000902 cell morphogenesis
GO:0001822 kidney development
GO:0006833 water transport
GO:0015840 urea transport
GO:0030855 epithelial cell differentiation
GO:0055075 potassium ion homeostasis
GO:0055078 sodium ion homeostasis
GO:0060157 urinary bladder development
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022435
View Gene Order
ENSBTAG00000009913
Not yet available
Cross-References
SwissProt O75631
TrEMBL
UniProt Splice Variant
Entrez Gene 7380
UniGene Hs.632787
RefSeq NM_001167574 NM_006953
HUGO HGNC:12580
OMIM 611559
CCDS CCDS14064 CCDS54539
HPRD
IMGT
EMBL AB010116 AB010637 AF085808 AL008718 BC069544 BC108900 CR456608
GenPept AAC34888 AAH69544 AAI08901 BAA25678 BAA31460 CAG30494 CAI17948 CAQ08673
RNA Seq Atlas 7380

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca