Homo sapiens Gene: ADAMTS16
Summary
InnateDB Gene IDBG-11455.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS16
Gene Name ADAM metallopeptidase with thrombospondin type 1 motif, 16
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145536
Encoded Proteins
ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:5140330-5320304
Strand Forward strand
Band p15.32
Transcripts
ENST00000274181 ENSP00000274181
ENST00000433402
ENST00000511368 ENSP00000421631
ENST00000513709
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.619000 Hs.661915
RefSeq NM_139056
HUGO
OMIM
CCDS CCDS43299
HPRD 06331
IMGT
EMBL
GenPept
RNA Seq Atlas