Version 5.4
| Homo sapiens Gene: IL32 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-11512.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | IL32 | ||||||||||||||||||
| Gene Name | interleukin 32 | ||||||||||||||||||
| Synonyms | IL-32alpha; IL-32beta; IL-32delta; IL-32gamma; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000008517 | ||||||||||||||||||
| Encoded Proteins |
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
interleukin 32
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| InnateDB Annotation | |||||||||||||||||||
| Summary |
IL32 enhances host immunity to Mycobacterium tuberculosis.
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| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 16:3065297-3082192 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p13.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_001012631 NM_001012632 NM_001012633 NM_001012634 NM_001012635 NM_001012636 NM_001012718 NM_004221 XM_005255686 | ||||||||||||||||||
| HUGO | |||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS32377 CCDS32378 CCDS32379 CCDS45394 | ||||||||||||||||||
| HPRD | 09346 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||