Version 5.4
Homo sapiens Gene: ATP8B4
Summary
InnateDB Gene IDBG-11542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP8B4
Gene Name ATPase, class I, type 8B, member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000104043
Encoded Proteins
IDBP-11544
ATPase, class I, type 8B, member 4
IDBP-583131
ATPase, class I, type 8B, member 4
IDBP-602690
ATPase, class I, type 8B, member 4
IDBP-586889
ATPase, class I, type 8B, member 4
IDBP-601584
ATPase, class I, type 8B, member 4
IDBP-591497
ATPase, class I, type 8B, member 4
IDBP-587295
ATPase, class I, type 8B, member 4
IDBP-587946
ATPase, class I, type 8B, member 4
IDBP-583747
ATPase, class I, type 8B, member 4
IDBP-601445
ATPase, class I, type 8B, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the cation transport ATPase (P-type) family and type IV subfamily. The encoded protein is involved in phospholipid transport in the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:49858238-50182817
Strand Reverse strand
Band q21.2
Transcripts
ENST00000284509 ENSP00000284509
ENST00000558498 ENSP00000452663
ENST00000559726 ENSP00000453229
ENST00000559829 ENSP00000453169
ENST00000560479 ENSP00000453070
ENST00000557955 ENSP00000453690
ENST00000558906 ENSP00000452956
ENST00000558203
ENST00000560354
ENST00000560161
ENST00000561385
ENST00000559998
ENST00000561104
ENST00000558458 ENSP00000453482
ENST00000558959
ENST00000560437
ENST00000558024 ENSP00000453143
ENST00000558829 ENSP00000453539
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005524 ATP binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 cation transport
GO:0008152 metabolic process
GO:0015914 phospholipid transport
GO:0045332 phospholipid translocation
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060131
View Gene Order
ENSBTAG00000011936
Not yet available
Pathways
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.511311 Hs.717945
RefSeq NM_024837 XM_006720693 XM_006720694 XM_006720695
HUGO
OMIM
CCDS CCDS32238
HPRD 10681
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca