Version 5.4
Homo sapiens Gene: CGGBP1
Summary
InnateDB Gene IDBG-115757.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CGGBP1
Gene Name CGG triplet repeat binding protein 1
Synonyms CGGBP; p20-CGGBP
Species Homo sapiens
Ensembl Gene ENSG00000163320
Encoded Proteins
IDBP-233185
CGG triplet repeat binding protein 1
IDBP-233184
CGG triplet repeat binding protein 1
IDBP-479856
CGG triplet repeat binding protein 1
IDBP-478852
CGG triplet repeat binding protein 1
IDBP-481884
CGG triplet repeat binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:88051944-88149885
Strand Reverse strand
Band p11.1
Transcripts
ENST00000309534 ENSP00000381428
ENST00000398392 ENSP00000381429
ENST00000482016 ENSP00000420374
ENST00000462901 ENSP00000418769
ENST00000467332 ENSP00000419459
ENST00000474441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003690 double-stranded DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054604
View Gene Order
ENSBTAG00000046959
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.444818 Hs.601699 Hs.601727 Hs.622366
RefSeq NM_001008390 NM_001195308 NM_003663
HUGO
OMIM
CCDS CCDS43111
HPRD 04529
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca