Version 5.4
Homo sapiens Gene: RP9
Summary
InnateDB Gene IDBG-11810.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RP9
Gene Name retinitis pigmentosa 9 (autosomal dominant)
Synonyms PAP-1; PAP1
Species Homo sapiens
Ensembl Gene ENSG00000164610
Encoded Proteins
IDBP-11812
retinitis pigmentosa 9 (autosomal dominant)
IDBP-371503
retinitis pigmentosa 9 (autosomal dominant)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:33094797-33109401
Strand Reverse strand
Band p14.3
Transcripts
ENST00000297157 ENSP00000297157
ENST00000448915 ENSP00000411577
ENST00000474370
ENST00000492391
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008380 RNA splicing
GO:0050890 cognition
Cellular Component
GO:0005634 nucleus
GO:0005785 signal recognition particle receptor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032239
View Gene Order
ENSBTAG00000032598
Not yet available
Cross-References
SwissProt Q8TA86
TrEMBL C9J6V2
UniProt Splice Variant
Entrez Gene 6100
UniGene Hs.326805 Hs.593431
RefSeq NM_203288
HUGO HGNC:10288
OMIM 607331
CCDS CCDS5440
HPRD
IMGT
EMBL AC074338 AX016710 BC025928
GenPept AAH25928
RNA Seq Atlas 6100

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca