Version 5.4
Homo sapiens Gene: BSG
Summary
InnateDB Gene IDBG-12353.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BSG
Gene Name basigin (Ok blood group)
Synonyms 5F7; CD147; EMMPRIN; M6; OK; TCSF
Species Homo sapiens
Ensembl Gene ENSG00000172270
Encoded Proteins
IDBP-12355
basigin (Ok blood group)
IDBP-12357
basigin (Ok blood group)
IDBP-12359
basigin (Ok blood group)
IDBP-813545
basigin (Ok blood group)
IDBP-813561
basigin (Ok blood group)
IDBP-761836
IDBP-813559
basigin (Ok blood group)
IDBP-813555
basigin (Ok blood group)
IDBP-813556
basigin (Ok blood group)
IDBP-813557
basigin (Ok blood group)
IDBP-813558
basigin (Ok blood group)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:571309-583493
Strand Forward strand
Band p13.3
Transcripts
ENST00000353555 ENSP00000343809
ENST00000346916 ENSP00000344707
ENST00000333511 ENSP00000333769
ENST00000545507 ENSP00000473664
ENST00000574970
ENST00000576984 ENSP00000473528
ENST00000573216 ENSP00000458665
ENST00000576925
ENST00000573784 ENSP00000473393
ENST00000572899
ENST00000571735
ENST00000590218
ENST00000612317 ENSP00000483737
ENST00000613627 ENSP00000484849
ENST00000618006 ENSP00000478958
ENST00000614867 ENSP00000484624
ENST00000618112
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
Experimentally validated
Total 35 [view]
Protein-Protein 34 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005537 mannose binding
Biological Process
GO:0006090 pyruvate metabolic process
GO:0007166 cell surface receptor signaling pathway
GO:0007566 embryo implantation
GO:0007596 blood coagulation
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043434 response to peptide hormone
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:0046689 response to mercury ion
GO:0046697 decidualization
GO:0050900 leukocyte migration
GO:0051591 response to cAMP
GO:0072661 protein targeting to plasma membrane
Cellular Component
GO:0000139 Golgi membrane
GO:0002080 acrosomal membrane
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0042383 sarcolemma
GO:0042470 melanosome
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023175
View Gene Order
ENSBTAG00000016648
Not yet available
Pathways
NETPATH
NetPath_23
TSH pathway
REACTOME
REACT_12560
Basigin interactions pathway
REACT_12051
Cell surface interactions at the vascular wall pathway
REACT_13552
Integrin cell surface interactions pathway
REACT_2071
Pyruvate metabolism pathway
REACT_118779
Extracellular matrix organization pathway
REACT_1046
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
REACT_118572
Degradation of the extracellular matrix pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
syndecan_1_pathway
Syndecan-1-mediated signaling events
Cross-References
SwissProt P35613
TrEMBL B4DY23 I3L192 Q54A51 R4GMX5 R4GN83
UniProt Splice Variant
Entrez Gene 682
UniGene Hs.501293 Hs.716791
RefSeq NM_001728 NM_198589 NM_198590 NM_198591 XM_005259619
HUGO HGNC:1116
OMIM 109480
CCDS CCDS12032 CCDS12033 CCDS12034 CCDS58635
HPRD
IMGT
EMBL AB072923 AB085790 AB091680 AC005559 AC009005 AF042848 AF042849 AF042850 AF042851 AF042852 AF042853 AF042854 AF548371 AK093337 AK302231 AY358113 AY942196 BC009040 CH471242 D45131 GU557064 GU557065 L10240 L20471 M87879 X64364
GenPept AAA68936 AAA91084 AAB41120 AAC33279 AAD10704 AAH09040 AAN40694 AAQ88480 AAX20110 ADD31881 ADD31882 BAA08109 BAB88938 BAC67168 BAC76828 BAG52693 BAG63585 CAA45716 EAW61180 EAW61181 EAW61185 EAW61186
RNA Seq Atlas 682

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca