Version 5.4
Homo sapiens Gene: RNMT
Summary
InnateDB Gene IDBG-1256.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNMT
Gene Name RNA (guanine-7-) methyltransferase
Synonyms hCMT1c; MET; RG7MT1
Species Homo sapiens
Ensembl Gene ENSG00000101654
Encoded Proteins
IDBP-1258
RNA (guanine-7-) methyltransferase
IDBP-1260
RNA (guanine-7-) methyltransferase
IDBP-601190
RNA (guanine-7-) methyltransferase
IDBP-725791
IDBP-725970
IDBP-727136
IDBP-727727
IDBP-726980
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:13726660-13764558
Strand Forward strand
Band p11.21
Transcripts
ENST00000262173 ENSP00000262173
ENST00000383314 ENSP00000372804
ENST00000543302 ENSP00000446426
ENST00000593007 ENSP00000468261
ENST00000592764 ENSP00000466111
ENST00000588417
ENST00000591746 ENSP00000467475
ENST00000589866 ENSP00000466252
ENST00000588457 ENSP00000467171
ENST00000591922
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004482 mRNA (guanine-N7-)-methyltransferase activity
GO:0005515 protein binding
GO:0008168 methyltransferase activity
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0008152 metabolic process
GO:0010467 gene expression
GO:0016032 viral process
GO:0036265 RNA (guanine-N7)-methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005845 mRNA cap binding complex
GO:0043235 receptor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000009535
View Gene Order
ENSBTAG00000009142
Not yet available
Pathways
NETPATH
REACTOME
REACT_1470
mRNA Capping pathway
REACT_975
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_6237
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt O43148
TrEMBL F5H2D9 K7EP06 K7EPP5 Q9UEB8
UniProt Splice Variant
Entrez Gene 8731
UniGene Hs.592347 Hs.623549 Hs.8086
RefSeq NM_003799 XM_005258160 XM_005258162 XM_006722361
HUGO HGNC:10075
OMIM 603514
CCDS CCDS11867
HPRD 04622
IMGT
EMBL AB007858 AB020966 AB022604 AB022605 AB022606 AF067791 AP001525 BC036798 CH471113 EF445026
GenPept AAC63269 AAH36798 ACA06068 BAA23694 BAA74462 BAA74463 BAA74464 BAA82447 EAX01505 EAX01506
RNA Seq Atlas 8731

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca