Version 5.4
Homo sapiens Gene: DOCK5
Summary
InnateDB Gene IDBG-12661.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOCK5
Gene Name dedicator of cytokinesis 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147459
Encoded Proteins
IDBP-12663
dedicator of cytokinesis 5
IDBP-294882
dedicator of cytokinesis 5
IDBP-364425
dedicator of cytokinesis 5
IDBP-473965
dedicator of cytokinesis 5
IDBP-479224
dedicator of cytokinesis 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:25184723-25418082
Strand Forward strand
Band p21.2
Transcripts
ENST00000276440 ENSP00000276440
ENST00000410074 ENSP00000387036
ENST00000444569 ENSP00000414125
ENST00000481100 ENSP00000429737
ENST00000495236
ENST00000478099
ENST00000487948
ENST00000467709 ENSP00000428479
ENST00000481728
ENST00000463457
ENST00000521405
ENST00000479547
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044447
View Gene Order
ENSBTAG00000015513
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
INOH website
Integrin signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.195403 Hs.700090 Hs.717863
RefSeq NM_024940 XM_005273651 XM_006716402
HUGO
OMIM
CCDS CCDS6047
HPRD 09925
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca