Version 5.4
Mus musculus Gene: Dtnb
Summary
InnateDB Gene IDBG-127748.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dtnb
Gene Name dystrobrevin, beta
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000071454
Encoded Proteins
IDBP-127750
dystrobrevin, beta
IDBP-127754
dystrobrevin, beta
IDBP-622316
dystrobrevin, beta
IDBP-622318
dystrobrevin, beta
IDBP-622326
dystrobrevin, beta
IDBP-622328
dystrobrevin, beta
IDBP-622329
dystrobrevin, beta
IDBP-622332
dystrobrevin, beta
IDBP-622333
dystrobrevin, beta
IDBP-622334
dystrobrevin, beta
IDBP-622335
dystrobrevin, beta
IDBP-622337
dystrobrevin, beta
IDBP-622339
dystrobrevin, beta
IDBP-622340
dystrobrevin, beta
IDBP-622343
dystrobrevin, beta
IDBP-622344
dystrobrevin, beta
IDBP-622345
dystrobrevin, beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138101:
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:3572381-3781796
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000077930 ENSMUSP00000077085
ENSMUST00000101637 ENSMUSP00000099161
ENSMUST00000173199 ENSMUSP00000134392
ENSMUST00000164578 ENSMUSP00000126194
ENSMUST00000173483 ENSMUSP00000134390
ENSMUST00000164607 ENSMUSP00000128230
ENSMUST00000174479 ENSMUSP00000133702
ENSMUST00000168806
ENSMUST00000173240 ENSMUSP00000133722
ENSMUST00000174639 ENSMUSP00000133601
ENSMUST00000174290 ENSMUSP00000133697
ENSMUST00000173524
ENSMUST00000174663 ENSMUSP00000134146
ENSMUST00000173736 ENSMUSP00000134519
ENSMUST00000173998 ENSMUSP00000133774
ENSMUST00000174109 ENSMUSP00000134151
ENSMUST00000174547 ENSMUSP00000133927
ENSMUST00000172598 ENSMUSP00000134124
ENSMUST00000173074
ENSMUST00000173498
ENSMUST00000172504
ENSMUST00000173542 ENSMUSP00000134036
ENSMUST00000172735
ENSMUST00000174414
ENSMUST00000174293
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138101
View Gene Order
ENSBTAG00000021072
Not yet available
Cross-References
SwissProt
TrEMBL G3UYD1
UniProt Splice Variant
Entrez Gene 13528
UniGene Mm.286202
RefSeq NM_001162465 NM_007886 XM_006514958 XM_006514959
OMIM
CCDS CCDS36396 CCDS49015
HPRD
IMGT
MGI ID MGI:1203728
MGI Symbol Dtnb
EMBL AC155273 CR974568
GenPept
RNA Seq Atlas 13528

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca