Mus musculus Gene: Gng11
Summary
InnateDB Gene IDBG-127883.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gng11
Gene Name guanine nucleotide binding protein (G protein), gamma 11
Synonyms 0610037B21Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000032766
Encoded Proteins
guanine nucleotide binding protein (G protein), gamma 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127920:
This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:4003943-4008445
Strand Forward strand
Band A1
Transcripts
ENSMUST00000031670 ENSMUSP00000031670
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005834 heterotrimeric G-protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Glucagon-type ligand receptors pathway
Signaling by GPCR pathway
Glucagon signaling in metabolic regulation pathway
Class B/2 (Secretin family receptors) pathway
Integration of energy metabolism pathway
Metabolism pathway
Aquaporin-mediated transport pathway
Regulation of insulin secretion pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
GPCR ligand binding pathway
Transmembrane transport of small molecules pathway
Signal Transduction pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
KEGG
Chemokine signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Prostacyclin signalling through prostacyclin receptor pathway
Platelet homeostasis pathway
ADP signalling through P2Y purinoceptor 12 pathway
ADP signalling through P2Y purinoceptor 1 pathway
Thromboxane signalling through TP receptor pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (i) signalling events pathway
G beta:gamma signalling through PI3Kgamma pathway
G beta:gamma signalling through PLC beta pathway
G alpha (12/13) signalling events pathway
G alpha (s) signalling events pathway
G alpha (z) signalling events pathway
Glucagon-type ligand receptors pathway
Class B/2 (Secretin family receptors) pathway
G-protein activation pathway
Opioid Signalling pathway
Presynaptic function of Kainate receptors pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Regulation of insulin secretion pathway
Glucagon signaling in metabolic regulation pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Activation of Kainate Receptors upon glutamate binding pathway
Transmission across Chemical Synapses pathway
GPCR ligand binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Signal amplification pathway
Aquaporin-mediated transport pathway
Hemostasis pathway
Aquaporin-mediated transport pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Regulation of insulin secretion pathway
Glucagon-type ligand receptors pathway
Signaling by GPCR pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Signal Transduction pathway
GPCR ligand binding pathway
Metabolism pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Glucagon signaling in metabolic regulation pathway
Class B/2 (Secretin family receptors) pathway
KEGG
Chemokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt P61953
TrEMBL
UniProt Splice Variant
Entrez Gene 66066
UniGene
RefSeq NM_025331
OMIM
CCDS CCDS39419
HPRD
IMGT
MGI ID MGI:1913316
MGI Symbol Gng11
EMBL AK002765 AK009529 BC039062 BC040065
GenPept AAH39062 AAH40065 BAB22340 BAB26342
RNA Seq Atlas 66066