Mus musculus Gene: Nt5c1b
Summary
InnateDB Gene IDBG-128655.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nt5c1b
Gene Name 5'-nucleotidase, cytosolic IB
Synonyms 4921514H13Rik; AIRP; CN-IB
Species Mus musculus
Ensembl Gene ENSMUSG00000020622
Encoded Proteins
5'-nucleotidase, cytosolic IB
5'-nucleotidase, cytosolic IB
5'-nucleotidase, cytosolic IB
5'-nucleotidase, cytosolic IB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185013:
This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010] Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:10369973-10390173
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000002456 ENSMUSP00000002456
ENSMUST00000118657 ENSMUSP00000112694
ENSMUST00000147323 ENSMUSP00000117869
ENSMUST00000143739 ENSMUSP00000123105
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0008253 5'-nucleotidase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009117 nucleotide metabolic process
GO:0016311 dephosphorylation
GO:0046085 adenosine metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Purine metabolism pathway
Metabolism pathway
Metabolism of nucleotides pathway
Purine catabolism pathway
KEGG
Nicotinate and nicotinamide metabolism pathway
Pyrimidine metabolism pathway
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Purine catabolism pathway
Metabolism of nucleotides pathway
Purine metabolism pathway
Metabolism pathway
KEGG
Pyrimidine metabolism pathway
Nicotinate and nicotinamide metabolism pathway
Purine metabolism pathway
INOH
Nicotinate Nicotinamide metabolism pathway
Purine nucleotides nucleosides metabolism pathway
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.272843
RefSeq NM_027588 XM_006515207 XM_006515209 XM_006515210 XM_006515212
OMIM
CCDS CCDS25810
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas