Version 5.4
Mus musculus Gene: Shroom4
Summary
InnateDB Gene IDBG-128787.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Shroom4
Gene Name shroom family member 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000068270
Encoded Proteins
IDBP-128789
shroom family member 4
IDBP-128793
shroom family member 4
IDBP-621308
shroom family member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158352:
This gene encodes a member of the APX/Shroom family, which contain an N-terminal PDZ domain and a C-terminal ASD2 motif. The encoded protein may play a role in cytoskeletal architecture. Mutations in this gene have been linked to Stocco dos Santos X-linked mental retardation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:6399854-6637448
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000103005 ENSMUSP00000100070
ENSMUST00000089520 ENSMUSP00000086949
ENSMUST00000143641 ENSMUSP00000131806
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0000902 cell morphogenesis
GO:0007015 actin filament organization
GO:0007420 brain development
GO:0050890 cognition
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0009898 cytoplasmic side of plasma membrane
GO:0009925 basal plasma membrane
GO:0015629 actin cytoskeleton
GO:0016324 apical plasma membrane
GO:0016460 myosin II complex
GO:0030864 cortical actin cytoskeleton
GO:0031941 filamentous actin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000158352
View Gene Order
ENSBTAG00000002996
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.23208
RefSeq NM_001040459 XM_006527547 XM_006527548 XM_006527549
OMIM
CCDS CCDS29959
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca