Version 5.4
Mus musculus Gene: Ptprz1
Summary
InnateDB Gene IDBG-129593.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptprz1
Gene Name protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms AI850339; DSD-1-PG; PTPbeta; Ptprz; Ptpz; PTPzeta; Rptpbeta; RPTPz
Species Mus musculus
Ensembl Gene ENSMUSG00000068748
Encoded Proteins
IDBP-129595
protein tyrosine phosphatase, receptor type Z, polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106278:
This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:22875502-23052916
Strand Forward strand
Band A3.1
Transcripts
ENSMUST00000090568 ENSMUSP00000088056
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006470 protein dephosphorylation
GO:0007409 axonogenesis
GO:0007611 learning or memory
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0048709 oligodendrocyte differentiation
GO:0070445 regulation of oligodendrocyte progenitor proliferation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0072534 perineuronal net
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106278
View Gene Order
ENSBTAG00000012119
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05120
Epithelial cell signaling in Helicobacter pylori infection pathway
INOH
PID NCI
Cross-References
SwissProt B9EKR1
TrEMBL Q8C4M8 Q99LN6
UniProt Splice Variant
Entrez Gene 19283
UniGene Mm.401336 Mm.41639 Mm.451032 Mm.488025
RefSeq NM_001081306 XM_006505012 XM_006505013 XM_006505014
OMIM
CCDS CCDS39437
HPRD
IMGT
MGI ID MGI:97816
MGI Symbol Ptprz1
EMBL AC133599 AC134445 AK081698 BC002298 BC151071
GenPept AAH02298 AAI51072 BAC38299
RNA Seq Atlas 19283

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca