InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp6v1c2

Summary

InnateDB Gene

IDBG-129661.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp6v1c2

Gene Name

ATPase, H+ transporting, lysosomal V1 subunit C2

Synonyms

1110038G14Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020566

Encoded Proteins

IDBP-129663

ATPase, H+ transporting, lysosomal V1 subunit C2

IDBP-129665

ATPase, H+ transporting, lysosomal V1 subunit C2

IDBP-534164

ATPase, H+ transporting, lysosomal V1 subunit C2

IDBP-535344

ATPase, H+ transporting, lysosomal V1 subunit C2

IDBP-537411

ATPase, H+ transporting, lysosomal V1 subunit C2

IDBP-533582

ATPase, H+ transporting, lysosomal V1 subunit C2

IDBP-536866

ATPase, H+ transporting, lysosomal V1 subunit C2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143882:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:17284721-17329359

Strand

Reverse strand

Band

A1.1

Transcripts

ENSMUST00000095820	ENSMUSP00000093500
ENSMUST00000020884	ENSMUSP00000020884
ENSMUST00000140751	ENSMUSP00000123415
ENSMUST00000156727	ENSMUSP00000117139
ENSMUST00000153090	ENSMUSP00000119686
ENSMUST00000127185	ENSMUSP00000118635
ENSMUST00000143131	ENSMUSP00000117993

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0046983	protein dimerization activity