Version 5.4
| Mus musculus Gene: Pdzd2 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-130051.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Pdzd2 | ||||||
| Gene Name | PDZ domain containing 2 | ||||||
| Synonyms | 4930537L06Rik; A930022H17Rik; Gm82; mKIAA0300; Pdzk3 | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000022197 | ||||||
| Encoded Proteins |
PDZ domain containing 2
PDZ domain containing 2
PDZ domain containing 2
PDZ domain containing 2
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133401:
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 15:12359711-12739924 | ||||||
| Strand | Reverse strand | ||||||
| Band | A1 | ||||||
| Transcripts | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | E9Q1M1 Q3UW81 Q80U45 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 68070 | ||||||
| UniGene | Mm.423205 Mm.475252 | ||||||
| RefSeq | NM_001081064 XM_006520159 XM_006520160 XM_006520161 XM_006520162 XM_006520163 XM_006520164 XM_006520168 XM_006520169 XM_006520170 XM_006520171 | ||||||
| OMIM | |||||||
| CCDS | CCDS37045 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1922394 | ||||||
| MGI Symbol | Pdzd2 | ||||||
| EMBL | AC133282 AC150660 AK122240 AK136542 | ||||||
| GenPept | BAC65522 BAE23036 | ||||||
| RNA Seq Atlas | 68070 | ||||||