Version 5.4
Mus musculus Gene: Casp12
Summary
InnateDB Gene IDBG-131695.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Casp12
Gene Name caspase 12
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025887
Encoded Proteins
IDBP-131697
caspase 12
IDBP-542823
caspase 12
IDBP-542545
caspase 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:5345430-5373032
Strand Forward strand
Band A1
Transcripts
ENSMUST00000027009 ENSMUSP00000027009
ENSMUST00000151788 ENSMUSP00000121565
ENSMUST00000149520
ENSMUST00000138308
ENSMUST00000151332 ENSMUSP00000122201
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0042981 regulation of apoptotic process
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu05010
Alzheimer's disease pathway
mmu04210
Apoptosis pathway
mmu05014
Amyotrophic lateral sclerosis (ALS) pathway
mmu05020
Prion diseases pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.42163
RefSeq NM_009808 XM_006509840
OMIM
CCDS CCDS22800
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca