Version 5.4
Mus musculus Gene: Mus81
Summary
InnateDB Gene IDBG-131880.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mus81
Gene Name MUS81 endonuclease homolog (yeast)
Synonyms 1200008A18Rik; AI182501; AW045863
Species Mus musculus
Ensembl Gene ENSMUSG00000024906
Encoded Proteins
IDBP-131882
MUS81 endonuclease homolog (yeast)
IDBP-540273
MUS81 endonuclease homolog (yeast)
IDBP-535575
MUS81 endonuclease homolog (yeast)
IDBP-540327
MUS81 endonuclease homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172732:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:5482345-5488402
Strand Reverse strand
Band A
Transcripts
ENSMUST00000025841 ENSMUSP00000025841
ENSMUST00000133436 ENSMUSP00000118580
ENSMUST00000124334 ENSMUSP00000114895
ENSMUST00000140365
ENSMUST00000147961
ENSMUST00000149908
ENSMUST00000146661
ENSMUST00000151932
ENSMUST00000154215
ENSMUST00000126471 ENSMUSP00000121435
ENSMUST00000144422
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0048257 3'-flap endonuclease activity
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0072429 response to intra-S DNA damage checkpoint signaling
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0045171 intercellular bridge
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172732
View Gene Order
ENSBTAG00000021456
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03440
Homologous recombination pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03440
Homologous recombination pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27697
RefSeq NM_027877 XM_006531838
OMIM
CCDS CCDS29467
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca