Version 5.4
Mus musculus Gene: Adi1
Summary
InnateDB Gene IDBG-132098.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adi1
Gene Name acireductone dioxygenase 1
Synonyms AL024210; Fe-ARD; MTCBP-1; Ni-ARD
Species Mus musculus
Ensembl Gene ENSMUSG00000020629
Encoded Proteins
IDBP-132100
acireductone dioxygenase 1
IDBP-542967
acireductone dioxygenase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182551:
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:28675231-28682175
Strand Forward strand
Band A2
Transcripts
ENSMUST00000020957 ENSMUSP00000020957
ENSMUST00000135772 ENSMUSP00000122965
ENSMUST00000138081
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0019509 L-methionine biosynthetic process from methylthioadenosine
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182551
View Gene Order
ENSBTAG00000005403
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_202492
Sulfur amino acid metabolism pathway
REACT_199099
Methionine salvage pathway pathway
REACT_253147
Metabolism of polyamines pathway
KEGG
mmu00270
Cysteine and methionine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75881
Methionine salvage pathway pathway
REACT_14820
Metabolism of polyamines pathway
REACT_115639
Sulfur amino acid metabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_226362
Metabolism of amino acids and derivatives pathway
REACT_202865
Methionine salvage pathway pathway
REACT_212045
Sulfur amino acid metabolism pathway
REACT_219139
Metabolism pathway
REACT_215919
Metabolism of polyamines pathway
KEGG
hsa00270
Cysteine and methionine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q99JT9
TrEMBL F7ARY2
UniProt Splice Variant
Entrez Gene 104923
UniGene Mm.291504
RefSeq NM_134052
OMIM
CCDS CCDS25853
HPRD
IMGT
MGI ID MGI:2144929
MGI Symbol Adi1
EMBL AC136986 AK145831 BC005695
GenPept AAH05695 BAE26682
RNA Seq Atlas 104923

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca