Homo sapiens Gene: MARCH11
Summary
InnateDB Gene IDBG-13226.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARCH11
Gene Name membrane-associated ring finger (C3HC4) 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183654
Encoded Proteins
membrane-associated ring finger (C3HC4) 11
membrane-associated ring finger (C3HC4) 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:16067139-16180762
Strand Reverse strand
Band p15.1
Transcripts
ENST00000332432 ENSP00000333181
ENST00000507111 ENSP00000424425
ENST00000505509
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 441061
UniGene Hs.662216
RefSeq NM_001102562
HUGO HGNC:33609
OMIM 613338
CCDS CCDS47192
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 441061