Mus musculus Gene: Nup43
Summary
InnateDB Gene IDBG-132439.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nup43
Gene Name nucleoporin 43
Synonyms 2610016K01Rik; 2610529I12Rik; AA409950; p42
Species Mus musculus
Ensembl Gene ENSMUSG00000040034
Encoded Proteins
nucleoporin 43
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120253:
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:7667503-7678881
Strand Forward strand
Band A1
Transcripts
ENSMUST00000040135 ENSMUSP00000046732
ENSMUST00000162346
ENSMUST00000162527
ENSMUST00000161060
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0031080 nuclear pore outer ring
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Nuclear Envelope Breakdown pathway
Cell Cycle, Mitotic pathway
Disease pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Separation of Sister Chromatids pathway
SLC-mediated transmembrane transport pathway
Resolution of Sister Chromatid Cohesion pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Cell Cycle pathway
Metabolism pathway
M Phase pathway
Transcriptional regulation by small RNAs pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Glucose transport pathway
Transmembrane transport of small molecules pathway
Hexose transport pathway
Glycogen storage diseases pathway
Gene Expression pathway
Regulatory RNA pathways pathway
Mitotic Prophase pathway
Myoclonic epilepsy of Lafora pathway
Mitotic Anaphase pathway
Metabolism of carbohydrates pathway
KEGG
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
ISG15 antiviral mechanism pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Glucose transport pathway
Hexose transport pathway
Nuclear import of Rev protein pathway
Vpr-mediated nuclear import of PICs pathway
Rev-mediated nuclear export of HIV RNA pathway
Viral Messenger RNA Synthesis pathway
Late Phase of HIV Life Cycle pathway
Transmembrane transport of small molecules pathway
Influenza Infection pathway
Interactions of Vpr with host cellular proteins pathway
Myoclonic epilepsy of Lafora pathway
Antiviral mechanism by IFN-stimulated genes pathway
Cytokine Signaling in Immune system pathway
Metabolism of carbohydrates pathway
Transcriptional regulation by small RNAs pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Influenza Viral RNA Transcription and Replication pathway
Interferon Signaling pathway
Cell Cycle pathway
Immune System pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Anaphase pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
Influenza Life Cycle pathway
Metabolism pathway
Host Interactions of HIV factors pathway
SLC-mediated transmembrane transport pathway
Interactions of Rev with host cellular proteins pathway
Gene Expression pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Glycogen storage diseases pathway
Mitotic Metaphase and Anaphase pathway
Regulatory RNA pathways pathway
KEGG
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.299887 Mm.460316
RefSeq NM_145706
OMIM
CCDS CCDS48493
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas