Version 5.4
Mus musculus Gene: Syt4
Summary
InnateDB Gene IDBG-132570.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syt4
Gene Name synaptotagmin IV
Synonyms SytIV
Species Mus musculus
Ensembl Gene ENSMUSG00000024261
Encoded Proteins
IDBP-132572
synaptotagmin IV
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the synaptotagmin family. Members of this family are multi-domained, integral membrane proteins of synaptic vesicles, and are thought to serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. This gene is primarily expressed in the nervous tissues. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:31437808-31447415
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000025110 ENSMUSP00000025110
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0001786 phosphatidylserine binding
GO:0005215 transporter activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030276 clathrin binding
Biological Process
GO:0006887 exocytosis
GO:0007269 neurotransmitter secretion
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0031339 negative regulation of vesicle fusion
GO:0045955 negative regulation of calcium ion-dependent exocytosis
GO:0048489 synaptic vesicle transport
Cellular Component
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0031045 dense core granule
GO:0043005 neuron projection
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132872
View Gene Order
ENSBTAG00000001801
Not yet available
Cross-References
SwissProt P40749
TrEMBL Q571C5
UniProt Splice Variant
Entrez Gene 20983
UniGene Mm.233846 Mm.490509
RefSeq NM_009308
OMIM
CCDS CCDS29109
HPRD
IMGT
MGI ID MGI:101759
MGI Symbol Syt4
EMBL AK032106 AK043985 AK050515 AK083960 AK148681 AK220264 BC058208 U10355
GenPept AAA20971 AAH58208 BAC27705 BAC31726 BAC34301 BAC39080 BAD90189 BAE28640
RNA Seq Atlas 20983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca