Version 5.4
Mus musculus Gene: Sash1
Summary
InnateDB Gene IDBG-132935.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sash1
Gene Name SAM and SH3 domain containing 1
Synonyms 1100001C18Rik; 2500002E12Rik; A330076K04Rik; mKIAA0790
Species Mus musculus
Ensembl Gene ENSMUSG00000015305
Encoded Proteins
IDBP-132937
SAM and SH3 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111961:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:8722219-8886070
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000015449 ENSMUSP00000015449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0019901 protein kinase binding
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0032947 protein complex scaffold
Biological Process
GO:0000209 protein polyubiquitination
GO:0010595 positive regulation of endothelial cell migration
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0043507 positive regulation of JUN kinase activity
GO:0045766 positive regulation of angiogenesis
GO:1900044 regulation of protein K63-linked ubiquitination
GO:1900745 positive regulation of p38MAPK cascade
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1902498 regulation of protein autoubiquitination
Cellular Component
GO:0016020 membrane
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111961
View Gene Order
ENSBTAG00000001826
Not yet available
Cross-References
SwissProt
TrEMBL F8VQK5 Q8BRY6
UniProt Splice Variant
Entrez Gene 70097
UniGene Mm.338275 Mm.474760
RefSeq NM_175155 XM_006512837 XM_006512838 XM_006512840 XM_006512841
OMIM
CCDS CCDS23692
HPRD
IMGT
MGI ID MGI:1917347
MGI Symbol Sash1
EMBL AC091522 AC153569 AK041048
GenPept BAC30797
RNA Seq Atlas 70097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca