Version 5.4
Mus musculus Gene: Gabrr2
Summary
InnateDB Gene IDBG-134359.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gabrr2
Gene Name gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000023267
Encoded Proteins
IDBP-134361
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
IDBP-265123
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
IDBP-534550
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
IDBP-532716
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111886:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:33062999-33095865
Strand Forward strand
Band A5
Transcripts
ENSMUST00000024035 ENSMUSP00000024035
ENSMUST00000108162 ENSMUSP00000103797
ENSMUST00000131920 ENSMUSP00000118514
ENSMUST00000147889 ENSMUSP00000114337
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004890 GABA-A receptor activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005254 chloride channel activity
GO:0019904 protein domain specific binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007601 visual perception
GO:0034220 ion transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030424 axon
GO:0034707 chloride channel complex
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111886
View Gene Order
ENSBTAG00000018435
Not yet available
Pathways
NETPATH
REACTOME
REACT_203664
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_198558
Ligand-gated ion channel transport pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_224131
GABA receptor activation pathway
REACT_259290
Neuronal System pathway
REACT_233318
Transmission across Chemical Synapses pathway
REACT_198557
GABA A (rho) receptor activation pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_25168
GABA A (rho) receptor activation pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_13685
Neuronal System pathway
REACT_25199
GABA receptor activation pathway
REACT_25300
Ion channel transport pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_223895
Ion channel transport pathway
REACT_221552
GABA receptor activation pathway
REACT_223058
Transmission across Chemical Synapses pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_220161
Ligand-gated ion channel transport pathway
REACT_202705
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_225032
Neuronal System pathway
REACT_219026
GABA A (rho) receptor activation pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 14409
UniGene Mm.6227
RefSeq NM_008076 XM_006537617
OMIM
CCDS CCDS18020
HPRD
IMGT
MGI ID MGI:95626
MGI Symbol Gabrr2
EMBL
GenPept
RNA Seq Atlas 14409

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca