Version 5.4
| Mus musculus Gene: Slc2a2 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-135094.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Slc2a2 | ||||||||||||
| Gene Name | solute carrier family 2 (facilitated glucose transporter), member 2 | ||||||||||||
| Synonyms | AI266973; Glut-2; Glut2 | ||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Gene | ENSMUSG00000027690 | ||||||||||||
| Encoded Proteins |
solute carrier family 2 (facilitated glucose transporter), member 2
solute carrier family 2 (facilitated glucose transporter), member 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163581:
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. [provided by RefSeq, Jul 2008] This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 3:28697903-28728356 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | A3 | ||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Disease pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Integration of energy metabolism pathway
Metabolism pathway
Regulation of insulin secretion pathway
Glucose transport pathway
Transmembrane transport of small molecules pathway
Hexose transport pathway
Glycogen storage diseases pathway
Regulation of gene expression in beta cells pathway
Developmental Biology pathway
Regulation of beta-cell development pathway
Facilitative Na+-independent glucose transporters pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
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| KEGG |
Maturity onset diabetes of the young pathway
Type II diabetes mellitus pathway
Carbohydrate digestion and absorption pathway
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| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Facilitative Na+-independent glucose transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Glucose transport pathway
Hexose transport pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Regulation of gene expression in beta cells pathway
Transmembrane transport of small molecules pathway
Developmental Biology pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Regulation of beta-cell development pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
Disease pathway
Glycogen storage diseases pathway
Metabolism of carbohydrates pathway
SLC-mediated transmembrane transport pathway
Hexose transport pathway
Regulation of insulin secretion pathway
Myoclonic epilepsy of Lafora pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Regulation of gene expression in beta cells pathway
Regulation of beta-cell development pathway
Facilitative Na+-independent glucose transporters pathway
Glucose transport pathway
Glycogen storage diseases pathway
Metabolism pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Disease pathway
Developmental Biology pathway
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| KEGG |
Maturity onset diabetes of the young pathway
Type II diabetes mellitus pathway
Carbohydrate digestion and absorption pathway
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| INOH | |||||||||||||
| PID NCI |
FOXA2 and FOXA3 transcription factor networks
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| Cross-References | |||||||||||||
| SwissProt | P14246 | ||||||||||||
| TrEMBL | E9PXR7 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 20526 | ||||||||||||
| UniGene | Mm.18443 Mm.399808 | ||||||||||||
| RefSeq | NM_031197 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS50880 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| MGI ID | MGI:1095438 | ||||||||||||
| MGI Symbol | Slc2a2 | ||||||||||||
| EMBL | AC121268 AK005068 AK165430 BC034675 S77926 X15684 X16986 X78722 | ||||||||||||
| GenPept | AAB20847 AAH34675 BAB23792 BAE38184 CAA33719 CAA34855 CAA55368 | ||||||||||||
| RNA Seq Atlas | 20526 | ||||||||||||