Mus musculus Gene: Usp11
Summary
InnateDB Gene IDBG-135115.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Usp11
Gene Name ubiquitin specific peptidase 11
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031066
Encoded Proteins
ubiquitin specific peptidase 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102226:
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:20703906-20720539
Strand Forward strand
Band A1.3
Transcripts
ENSMUST00000033383 ENSMUSP00000033383
ENSMUST00000127294
ENSMUST00000137101
ENSMUST00000149960
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.
Predicted by orthology
Total 82 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Chaperonin-mediated protein folding pathway
Association of TriC/CCT with target proteins during biosynthesis pathway
Metabolism of proteins pathway
Protein folding pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TNFalpha pathway
REACTOME
Association of TriC/CCT with target proteins during biosynthesis pathway
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.34489
RefSeq NM_145628 XM_006527622
OMIM
CCDS CCDS53015
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas