Version 5.4
| Mus musculus Gene: Cga | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-135569.6 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | Cga | ||||||||||||||||
| Gene Name | glycoprotein hormones, alpha subunit | ||||||||||||||||
| Synonyms | aGSU; alpha-GSU; alphaGSU; alphaSU; CG-alpha; FSHA; GPHA1; GPHalpha; HCG; LHA; Tsha | ||||||||||||||||
| Species | Mus musculus | ||||||||||||||||
| Ensembl Gene | ENSMUSG00000028298 | ||||||||||||||||
| Encoded Proteins |
glycoprotein hormones, alpha subunit
glycoprotein hormones, alpha subunit
glycoprotein hormones, alpha subunit
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135346:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 4:34893779-34907370 | ||||||||||||||||
| Strand | Forward strand | ||||||||||||||||
| Band | A5 | ||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
G alpha (s) signalling events pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Hormone ligand-binding receptors pathway
Metabolism pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
Metabolism of amino acids and derivatives pathway
Peptide hormone metabolism pathway
Mineralocorticoid biosynthesis pathway
GPCR ligand binding pathway
Androgen biosynthesis pathway
Glycoprotein hormones pathway
Thyroxine biosynthesis pathway
Signal Transduction pathway
Metabolism of steroid hormones and vitamin D pathway
Amine-derived hormones pathway
Peptide hormone biosynthesis pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
GnRH signaling pathway pathway
Autoimmune thyroid disease pathway
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| INOH |
GPCR signaling pathway
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| PID NCI | |||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH |
TSH pathway
FSH pathway
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| REACTOME |
G alpha (s) signalling events pathway
Hormone ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Glycoprotein hormones pathway
Peptide hormone biosynthesis pathway
Mineralocorticoid biosynthesis pathway
Androgen biosynthesis pathway
Thyroxine biosynthesis pathway
Metabolism of lipids and lipoproteins pathway
Signaling by GPCR pathway
Amine-derived hormones pathway
Metabolism of steroid hormones and vitamin D pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Metabolism of proteins pathway
Metabolism of amino acids and derivatives pathway
GPCR ligand binding pathway
Metabolism pathway
Peptide hormone metabolism pathway
Peptide hormone metabolism pathway
Signaling by GPCR pathway
G alpha (s) signalling events pathway
Glycoprotein hormones pathway
Signal Transduction pathway
Peptide hormone biosynthesis pathway
Metabolism of proteins pathway
Metabolism of lipids and lipoproteins pathway
Mineralocorticoid biosynthesis pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Metabolism of steroid hormones and vitamin D pathway
Metabolism pathway
Class A/1 (Rhodopsin-like receptors) pathway
Hormone ligand-binding receptors pathway
Androgen biosynthesis pathway
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| KEGG |
GnRH signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
Autoimmune thyroid disease pathway
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| INOH |
GPCR signaling pathway
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| PID NCI |
Glucocorticoid receptor regulatory network
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| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | |||||||||||||||||
| RefSeq | NM_009889 XM_006537586 | ||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | CCDS18035 | ||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| MGI ID | |||||||||||||||||
| MGI Symbol | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||