Version 5.4
Mus musculus Gene: Slc6a14
Summary
InnateDB Gene IDBG-136056.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc6a14
Gene Name solute carrier family 6 (neurotransmitter transporter), member 14
Synonyms 1110007A17Rik; 9030613J17Rik; ATB0plus; CATB0plus
Species Mus musculus
Ensembl Gene ENSMUSG00000031089
Encoded Proteins
IDBP-136058
solute carrier family 6 (neurotransmitter transporter), member 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:21714896-21742355
Strand Forward strand
Band A2
Transcripts
ENSMUST00000033414 ENSMUSP00000033414
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005275 amine transmembrane transporter activity
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006836 neurotransmitter transport
GO:0006865 amino acid transport
GO:0009636 response to toxic substance
GO:0015837 amine transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0031526 brush border membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000000185
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253228
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_230460
Amino acid transport across the plasma membrane pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9JMA9
TrEMBL A1L359
UniProt Splice Variant
Entrez Gene 56774
UniGene Mm.253984
RefSeq NM_020049
OMIM
CCDS CCDS30051
HPRD
IMGT
MGI ID MGI:1890216
MGI Symbol Slc6a14
EMBL AB033285 AF161714 AF320226 AK018553 BC129908 BC129909 CH466625
GenPept AAD49320 AAI29909 AAI29910 AAK43541 BAA94300 BAB31272 EDL00718
RNA Seq Atlas 56774

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca