InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: CD9

Summary

InnateDB Gene

IDBG-13612.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD9

Gene Name

CD9 molecule

Synonyms

BTCC-1; DRAP-27; MIC3; MRP-1; TSPAN-29; TSPAN29

Species

Homo sapiens

Ensembl Gene

ENSG00000010278

Encoded Proteins

IDBP-13614

CD9 molecule

IDBP-13616

CD9 molecule

IDBP-13618

CD9 molecule

IDBP-13620

CD9 molecule

IDBP-602442

CD9 molecule

IDBP-811430

CD9 molecule

IDBP-811432

CD9 molecule

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:6199715-6238271

Strand

Forward strand

Band

p13.31

Transcripts

ENST00000382519	ENSP00000371959
ENST00000382518	ENSP00000371958
ENST00000009180	ENSP00000009180
ENST00000382515	ENSP00000371955
ENST00000481267
ENST00000543916
ENST00000536586	ENSP00000440985
ENST00000546073
ENST00000538834
ENST00000538418
ENST00000540891
ENST00000617871	ENSP00000482643
ENST00000610354	ENSP00000478288

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	38 [view]
Protein-Protein	37 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005515	protein binding

Biological Process

GO:0002576	platelet degranulation
GO:0006928	cellular component movement
GO:0007155	cell adhesion
GO:0007338	single fertilization
GO:0007342	fusion of sperm to egg plasma membrane
GO:0007420	brain development
GO:0007596	blood coagulation
GO:0008285	negative regulation of cell proliferation
GO:0009414	response to water deprivation
GO:0014003	oligodendrocyte development
GO:0030168	platelet activation
GO:0030913	paranodal junction assembly
GO:0032504	multicellular organism reproduction

Cellular Component

GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0031092	platelet alpha granule membrane
GO:0070062	extracellular vesicular exosome