Mus musculus Gene: Akr1d1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-136333.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | Akr1d1 | ||||||||||||||||||
Gene Name | aldo-keto reductase family 1, member D1 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||
Ensembl Gene | ENSMUSG00000038641 | ||||||||||||||||||
Encoded Proteins |
aldo-keto reductase family 1, member D1
aldo-keto reductase family 1, member D1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122787:
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 6:37530173-37568815 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | B1 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of bile acids and bile salts pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 27-hydroxycholesterol pathway
Bile acid and bile salt metabolism pathway
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KEGG |
Primary bile acid biosynthesis pathway
Steroid hormone biosynthesis pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 27-hydroxycholesterol pathway
Synthesis of bile acids and bile salts pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Metabolism pathway
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KEGG |
Steroid hormone biosynthesis pathway
Primary bile acid biosynthesis pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Mm.262635 | ||||||||||||||||||
RefSeq | NM_145364 XM_006505825 XM_006505827 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS20007 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
MGI ID | |||||||||||||||||||
MGI Symbol | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||