Mus musculus Gene: Fbxo18 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-136862.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Fbxo18 | ||||||||||||
Gene Name | F-box protein 18 | ||||||||||||
Synonyms | AU015756; Fbh1; Fbx18 | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000058594 | ||||||||||||
Encoded Proteins |
F-box protein 18
F-box protein 18
F-box protein 18
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134452:
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 2:11742573-11777582 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | A1 | ||||||||||||
Transcripts | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||
SwissProt | Q8K2I9 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 50755 | ||||||||||||
UniGene | Mm.24088 | ||||||||||||
RefSeq | NM_015792 XM_006497506 XM_006497507 XM_006497508 XM_006497509 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS15688 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | MGI:1354699 | ||||||||||||
MGI Symbol | Fbxo18 | ||||||||||||
EMBL | AF184275 AK003964 AK083118 BC004036 BC031393 | ||||||||||||
GenPept | AAF03151 AAH04036 AAH31393 BAB23095 BAC38767 | ||||||||||||
RNA Seq Atlas | 50755 | ||||||||||||