Version 5.4
Mus musculus Gene: Dock11
Summary
InnateDB Gene IDBG-137575.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dock11
Gene Name dedicator of cytokinesis 11
Synonyms 5033414A21Rik; 8030476J24; sph238; Zizimin2
Species Mus musculus
Ensembl Gene ENSMUSG00000031093
Encoded Proteins
IDBP-137577
dedicator of cytokinesis 11
IDBP-249994
dedicator of cytokinesis 11
IDBP-249998
dedicator of cytokinesis 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147251:
Gene Information
Type Protein coding
Genomic Location Chromosome X:35888832-36076562
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000033419 ENSMUSP00000033419
ENSMUST00000115266 ENSMUSP00000110921
ENSMUST00000115264 ENSMUSP00000110919
ENSMUST00000145757
ENSMUST00000140175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0017048 Rho GTPase binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0032319 regulation of Rho GTPase activity
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147251
View Gene Order
ENSBTAG00000006439
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
cdc42_reg_pathway
Regulation of CDC42 activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.32873
RefSeq NM_001009947 XM_006541406 XM_006541407 XM_006541408
OMIM
CCDS CCDS40923
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca