Version 5.4
| Mus musculus Gene: Nudt2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-137878.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Nudt2 | ||||||||
| Gene Name | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | ||||||||
| Synonyms | 2310051L06Rik; AA939917; APAH1 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000028443 | ||||||||
| Encoded Proteins |
nudix (nucleoside diphosphate linked moiety X)-type motif 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164978:
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 4:41465151-41480926 | ||||||||
| Strand | Forward strand | ||||||||
| Band | A5 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Pyrimidine metabolism pathway
Purine metabolism pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Pyrimidine metabolism pathway
Purine metabolism pathway
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| INOH |
Purine nucleotides nucleosides metabolism pathway
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| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P56380 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 66401 | ||||||||
| UniGene | Mm.28574 | ||||||||
| RefSeq | NM_025539 XM_006538165 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS18061 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1913651 | ||||||||
| MGI Symbol | Nudt2 | ||||||||
| EMBL | AK009933 AK018771 BC025153 | ||||||||
| GenPept | AAH25153 BAB26592 BAB31399 | ||||||||
| RNA Seq Atlas | 66401 | ||||||||