Version 5.4
Mus musculus Gene: Mrc1
Summary
InnateDB Gene IDBG-138187.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrc1
Gene Name mannose receptor, C type 1
Synonyms AW259686; CD206; MR
Species Mus musculus
Ensembl Gene ENSMUSG00000026712
Encoded Proteins
IDBP-138189
mannose receptor, C type 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 27220602
Expression of Cxcl13, Ifngr1, Retnla and Mrc1 distinguishes between large and small resident peritoneal macrophage subsets.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:14229414-14332057
Strand Forward strand
Band A2
Transcripts
ENSMUST00000028045 ENSMUSP00000028045
ENSMUST00000146168
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004888 transmembrane signaling receptor activity
GO:0005537 mannose binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007165 signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000038048
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt Q61830
TrEMBL Q2HZ94
UniProt Splice Variant
Entrez Gene 17533
UniGene Mm.2019
RefSeq NM_008625
OMIM
CCDS CCDS15700
HPRD
IMGT
MGI ID MGI:97142
MGI Symbol Mrc1
EMBL AK079897 AL845290 AL845434 BC141338 DQ358917 DQ358918 DQ358919 DQ358920 DQ358921 DQ358922 DQ358923 DQ358924 DQ358925 DQ358926 DQ358927 DQ358928 DQ358929 DQ358930 DQ358931 DQ358932 DQ358933 DQ358934 DQ358935 DQ358936 DQ358937 DQ358938 DQ358939 DQ358940 DQ358941 DQ358942 DQ358943 DQ358944 DQ358945 DQ358946 DQ358947 DQ358948 DQ358949 DQ358950 DQ358951 DQ358952 DQ358953 DQ358954 DQ358955 DQ358956 DQ358957 DQ358958 DQ358959 DQ358960 DQ358961 DQ358962 DQ358963 DQ358964 DQ358965 DQ358966 DQ358967 DQ358968 Z11974
GenPept AAI41339 ABC87985 ABC87986 BAC37778 CAA78028
RNA Seq Atlas 17533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca